Conveying the Role of Professional Farm Managers to Potential Clientele

Many farmland owners opt to work directly with farmer-tenants while others choose to hire a professional farm manager to assist in the management of their land. As absentee landownership increases and more landowners become less associated with farming, professional farm managers have increased opportunity to communicate their role to potential clientele. Some landowners have an opportunity to make the most of their situation by enlisting the services of a professional farm manager, but only if they know what can be expected from a professional farm manager. We discuss some of the benefits and disadvantages to landowners and tenants of professional farm management and how professional farm managers can convey these ideas to potential clients and assist landowners to choose the best farm manager for their farm.Farm Management,

Iodinated contrast media and cerebral hemorrhage after intravenous thrombolysis

<p>Background and Purpose: Iodinated contrast is increasingly used in CT perfusion or angiographic examinations in acute stroke. Increased risk of intracranial hemorrhage (ICH) complicating microcatheter contrast injections has recently been reported in the second Interventional Management of Stroke (IMS 2) trial with contrast toxicity potentially contributory.</p> <p>Methods: We reviewed clinical and radiological data on all patients treated with intravenous alteplase at a single center between May 2003 and November 2008.</p> <p>Results: Of 312 patients treated with intravenous alteplase, 69 (22.1%) received intravenous iodinated contrast in volumes between 50 and 150 mL. Incidence of symptomatic ICH defined as per European Cooperative Acute Stroke Study 2 was 16 of 312 (5.1%; 95% CI, 2.7% to 7.6%); among patients not given contrast, it was 12 of 243 (4.9%; 2.2% to 7.7%) compared with 4 of 69 (5.8%; 0.3% to 11.3%) in those given contrast. Incidence of symptomatic ICH defined as per Safe Implementation of Thrombolysis in Stroke-MOnitoring Study (SITS-MOST) criteria was 12 of 312 (3.9%; 1.7% to 6%), 9 of 243 (3.7%; 1.3% to 6%) among those not given contrast, and 3 of 69 (4.4%; 95% CI, -0.5% to 9.2%) among those given contrast. Patients with symptomatic ICH were older, had higher pretreatment National Institutes of Health Stroke Scale, and blood glucose than those without symptomatic ICH. In logistic regression analysis, pretreatment blood glucose was the only significant predictor of symptomatic ICH by either definition (OR, 1.23; 95% CI, 1.03 to 1.48 per mmol/L increment; P=0.024). Contrast administration or dose was not associated with symptomatic ICH.</p> <p>Conclusions: Intravenous iodinated contrast in doses typically required for CT angiography and perfusion imaging was not associated with symptomatic intracranial hemorrhage in patients treated with alteplase.</p&gt

Evolution and diversity of secretome genes in the apicomplexan parasite Theileria annulata

<b>BACKGROUND</b>: Little is known about how apicomplexan parasites have evolved to infect different host species and cell types. Theileria annulata and Theileria parva invade and transform bovine leukocytes but each species favours a different host cell lineage. Parasite-encoded proteins secreted from the intracellular macroschizont stage within the leukocyte represent a critical interface between host and pathogen systems. Genome sequencing has revealed that several Theileria-specific gene families encoding secreted proteins are positively selected at the inter-species level, indicating diversification between the species. We extend this analysis to the intra-species level, focusing on allelic diversity of two major secretome families. These families represent a well-characterised group of genes implicated in control of the host cell phenotype and a gene family of unknown function. To gain further insight into their evolution and function, this study investigates whether representative genes of these two families are diversifying or constrained within the T. annulata population. <b>RESULTS</b>: Strong evidence is provided that the sub-telomerically encoded SVSP family and the host-nucleus targeted TashAT family have evolved under contrasting pressures within natural T. annulata populations. SVSP genes were found to possess atypical codon usage and be evolving neutrally, with high levels of nucleotide substitutions and multiple indels. No evidence of geographical sub-structuring of allelic sequences was found. In contrast, TashAT family genes, implicated in control of host cell gene expression, are strongly conserved at the protein level and geographically sub-structured allelic sequences were identified among Tunisian and Turkish isolates. Although different copy numbers of DNA binding motifs were identified in alleles of TashAT proteins, motif periodicity was strongly maintained, implying conserved functional activity of these sites. <b>CONCLUSIONS</b>: This analysis provides evidence that two distinct secretome genes families have evolved under contrasting selective pressures. The data supports current hypotheses regarding the biological role of TashAT family proteins in the management of host cell phenotype that may have evolved to allow adaptation of T. annulata to a specific host cell lineage. We provide new evidence of extensive allelic diversity in representative members of the enigmatic SVSP gene family, which supports a putative role for the encoded products in subversion of the host immune response

Influences causing variation in butter-fat production

Citation: Baird, Wallace W. Influences causing variation in butter-fat production. Senior thesis, Kansas State Agricultural College, 1904.Morse Department of Special CollectionsIntroduction: It is a well known fact that changes in the weather, feed, care and treatment of the cow affects the production of butter-fat also, that the test and the amount of milk varies greatly from milking to milking with a single cow, while the average test from a herd varies but little. Where a great deal of milk is produced by a cow the test is apt to be low, and where there is little milk produced the test is usually high. The question of condi ti ons which affect the producti on of butter-fat is a complicated one in as much as one condi ti on may counteract the effect of another --for instance, good shelter and a little extra care will counteract the effect of severe weather, while rough handling will reduce the advantages obtained by good feeding. The reas on for mak ing this exper iment was that no experiment of the kind which covers a long period is on record. Twelve cows were selected from the College dairy herd --six of them thorough-breds, Jerseys, Holsteins and Ayrshires, and six of them grades and scrubs. The milk was carefully weighed after each milking and samples taken and tested. The time covered was one hundred thirty-seven days beginning with the 11th of December and ending the 25th of April. Five of the scrub cows were dropped during February and March and were replaced by four others, but the thorough-breds and one scrub were tested the whole time

Whose Bones are These?

The topic of this presentation will be on the preliminary findings of my independent study which is focusing on skeletal and archaeological remains obtained by my family a hundred years ago in Geneseo, New York. The presentation will look at the history of the region they were found and what was discovered by analyzing the remains and stone tools

Spencer Academy: the Choctaw "Harvard", 1842-1900

Thesis (M.A.)--University of Oklahoma, 1965.Includes bibliographical references (leaves 119-123

The early life of John Donne, 1572-1602 : a study of the biographical determinants of his writings

This thesis came about as a result of a search for a life of Donne to be used as background material for a study of the use of elisions in his poetry. It was with considerable surprise that I discovered the lack of any real biography of the poet since Sir Edmund Gosse's two volume attempt at the end of the last century. Since then there have been innumerable studies of one or another facet of Donne's life and work, but no one has attempted a serious work on the whole man. Hugh I'A. Fausset's Study in Discord, to which no references of any kind have been made in this was a poor restatement of Gosse's overly- romantic treatment of the poet without Gosse's fortunately firm framework of 17th Century Christian orthodoxy.Once determined on the subject, I had one great advantage that is often missing in modern scholarship, especially American scholarship. Much as I enjoyed and admired Donne's work, I had no special beliefs about either his life or work. There are many points made in this thesis which I did not at first believe but was forced to accept as I went along. Even while writing on such events as the Armada and Donne's reaction to it, I found my first thoughts to be incorrect. At no time did any prejudgements have so much force as to keep me from changing. Indeed there are some arguments which are still very fluid in my mind, but I have not put down any of these thoughts without finding sufficient proof. For example, I think it very likely that Donne wrote not only his Satyres between his two Essex voyages, but nearly all the Elegies as well, perhaps beginning with a translation of Ovid or Horace on the trip back from Cadiz. I have attempted to keep away from the romancing of Gosse, however, and have not recorded these thoughts unless there has been sufficient evidence.Whenever industry or interest flagged, there were always new articles or criticisms to awaken anger sufficient to carry on. The lack of full biographical treatment of Donne has led to a good deal of utter rot being printed about the man. Marius Bewley's last article in The Kenyon Review is a good example. His "psychological" criticisms seem to me to be ridiculous, but he is welcome to them. His completely wrong biographical data, however, merely angers me. If this thesis did nothing but show that Donne was not trained by Jesuits, it would be valuable. BBC broadcasts have shown a similar lack of knowledge about Donne. The Schools' broadcast for May 18, 1952, used material from Walton's biography of Donne which has been shown to be inaccurate. John Dowland's "Sweet, Stay awhile" has been announced as by Donne. And a program on the reading of Donne on the Third Programme has claimed that to read Donne correctly, one must be like him and feel with him - -this spoken by a voice which continued to mis-pronounce his name. It seems strange that after so much has been written on the subject and after Donne himself made the point so clear that the "official" pronunciation of his name should be so obviously wrong. Then there are the other problems of Donne scholarship which have led to so much error, particularly in the uncritical acceptance of the letters from the Burley MS. I have given as much attention to these problems as possible, but I have attempted to subordinate them to the main purpose of the thesis: to give as complete and as detailed a description of Donne's first thirty years as is possible from printed and manuscript material now available. As the Bibliography indicates, I have attempted to draw upon all sources for a study of Donne's entire life, for his later actions help to illuminate the young man

NEMA wire and cable standards development programs

The National Electrical Manufacturers Association (NEMA) is the nation's largest trade association for manufacturers of electrical equipment. Its member companies produce components, end-use equipment and systems for the generation, transmission, distribution, control and use of electricity. The wire and cable division is presented in 6 sections: building wire and cable, fabricated conductors, flexible cords, high performance wire and cable, magnet wire, and power and control cable. Participating companies are listed

Uniquely human CHRFAM7A gene increases the hematopoietic stem cell reservoir in mice and amplifies their inflammatory response.

A subset of genes in the human genome are uniquely human and not found in other species. One example is CHRFAM7A, a dominant-negative inhibitor of the antiinflammatory α7 nicotinic acetylcholine receptor (α7nAChR/CHRNA7) that is also a neurotransmitter receptor linked to cognitive function, mental health, and neurodegenerative disease. Here we show that CHRFAM7A blocks ligand binding to both mouse and human α7nAChR, and hypothesized that CHRFAM7A-transgenic mice would allow us to study its biological significance in a tractable animal model of human inflammatory disease, namely SIRS, the systemic inflammatory response syndrome that accompanies severe injury and sepsis. We found that CHRFAM7A increased the hematopoietic stem cell (HSC) reservoir in bone marrow and biased HSC differentiation to the monocyte lineage in vitro. We also observed that while the HSC reservoir was depleted in SIRS, HSCs were spared in CHRFAM7A-transgenic mice and that these mice also had increased immune cell mobilization, myeloid cell differentiation, and a shift to inflammatory monocytes from granulocytes in their inflamed lungs. Together, the findings point to a pathophysiological inflammatory consequence to the emergence of CHRFAM7A in the human genome. To this end, it is interesting to speculate that human genes like CHRFAM7A can account for discrepancies between the effectiveness of drugs like α7nAChR agonists in animal models and human clinical trials for inflammatory and neurodegenerative disease. The findings also support the hypothesis that uniquely human genes may be contributing to underrecognized human-specific differences in resiliency/susceptibility to complications of injury, infection, and inflammation, not to mention the onset of neurodegenerative disease

An Overview of the Upper Carboniferous Fossil Deposit at Linton, Ohio

Author Institution: Department of Paleobiology, National Museum of Natural History, Smithsonian Institution and Museum of Natural History, Princeton UniversityThe cannel coal that underlies the Upper Freeport coal (Westphalian D, Upper Carboniferous) at Linton in Jefferson County, Ohio, has yielded a remarkable fossil assemblage of at least 10 invertebrate taxa and nearly 40 vertebrate taxa. Spirorbid worms, crustaceans (primarily syncarids and conchostracans), and fishes (coelacanths, haplolepid palaeoniscoids, and xenacanth sharks) are the most abundant fossils in the deposit; small aquatic amphibians (including nectridean, temnospondyl, and aistopod species) are also common. Other arthropod and tetrapod taxa are exceedingly rare and possess obvious adaptations for terrestrial existence